@ARTICLE{muehlbacher06a,
  author = {F. M{\"u}hlbacher and C. Holm and H. Schiessel},
  title = {Controlled {DNA} compaction within chromatin: The tail-bridging effect},
  journal = {Europhys. Lett.},
  year = {2006},
  volume = {73},
  pages = {135--141},
  number = {1},
  abstract = {We study a mechanism underlying the attraction between nucleosomes,
	the fundamental packaging units of DNA inside the chromatin complex,
	by introducing a simple model of the nucleosome: the eight-tail colloid,
	a negatively charged sphere with eight oppo- sitely charged, flexible,
	grafted chains that represent the terminal histone tails. We demonstrate
	that our complexes are attracted via the formation of chain bridges
	and that this attraction can be tuned by changing the fraction of
	charged monomers on the tails. This suggests a physical mechanism
	of chromatin compaction where the degree of DNA condensation can
	be controlled via biochemical means, namely the acetylation and deacetylation
	of lysines in the histone tails.},
  bdsk-url-1 = {http://dx.doi.org/10.1209/epl/i2005-10351-4},
  date-modified = {2008-09-03 03:36:40 +0200},
  file = {muehlbacher06a.pdf:muehlbacher06a.pdf:PDF},
  owner = {holm},
  timestamp = {2006.10.03}
}